Anti-Denosumab Polyclonal Antibody - AT439014

Anti-Denosumab Polyclonal Antibody

Sizes: 50μg, 100μg

Catalogue Numbers: AT439014-50, AT439014-100

Citations, Manuals and MSDS Available upon request.

Host species: Rabbit

Specificity: The product is specific for Denosumab. This antibody serves as an excellent positive control for Denosumab immunogenicity (ADA) assays.

Immunogen: Denosumab

Form: Liquid

Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Clonality: Polyclonal

Isotype: IgG

Applications: ELISA

Target: Rabbit polyclonal to Prolia.

Purification: Purified by antigen affinity column.

Stability and Storage: The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.

Background: Denosumab with trade name Prolia, is an FDA-approved drug for the treatment of patients with osteoporosis, treatment-induced bone loss, metastases to bone, and giant cell tumor of bone. Denosumab is a fully human monoclonal antibody that works as a RANK ligand (RANKL) inhibitor. Denosumab can bind RANKL, preventing RANKL from activating RANK, its receptor on the osteoclast surface.

Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.