Anti-Ipilimumab Polyclonal Antibody - AB651014

Anti-Ipilimumab Polyclonal Antibody

Sizes: 50μg, 100μg

Catalogue Numbers: AB651014-50, AB651014-100

Citations, Manuals and MSDS Available upon request.

Host species: Rabbit

Specificity: The product is specific for Ipilimumab. This antibody serves as an excellent positive control for Ipilimumab immunogenicity (ADA) assays.

Immunogen: Ipilimumab

Form: Liquid

Storage buffer: 0.01M PBS, pH 7.4.

Clonality: Polyclonal

Isotype: IgG

Applications: ELISA

Target: Rabbit polyclonal to Yervoy.

Purification: Purified by antigen affinity column.

Stability and Storage: The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.

Background: Ipilimumab (Yervoy) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Ipilimumab works to activate the immune system by targeting CTLA-4 (Cytotoxic T-lymphocyte protein 4), a negative regulator of cytotoxic T-lymphocyte activity. Ipilimumab binds to CTLA-4, blocking the inhibitory signal, which allows the cytotoxic T-lymphocytes to destroy the cancer cells.

Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.