Anti-Ramucirumab Polyclonal Antibody
Sizes: 50μg, 100μg
Catalogue Numbers: AW338014-50, AW338014-100
Citations, Manuals and MSDS Available upon request.
Host species: Rabbit
Specificity: The product is specific for Ramucirumab. This antibody serves as an excellent positive control for Ramucirumab immunogenicity (ADA) assays.
Immunogen: Ramucirumab
Form: Liquid
Storage buffer: 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Clonality: Polyclonal
Isotype: IgG
Applications: ELISA
Purification: Antigen affinity purification.
Stability and Storage: The product can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
Background: Ramucirumab (LY3009806) is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of human endothelial cells.
Alternative Names: Rabbit polyclonal to REGN-10987.
Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.