Product Description

ANX13 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES11120-50, ES11120-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined, however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Target: ANX13

Specificity: ANX13 Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Detected in epithelial cells in colon and jejunum (at protein level), Detected in epithelial cells in jejunum,

Observed Band (KD): 34kD

Function: Domain: A pair of annexin repeats may form one binding site for calcium and phospholipid
Similarity: Belongs to the annexin family
Similarity: Contains 4 annexin repeats
Subcellular Location: Associated with the plasma membrane of undifferentiated, proliferating crypt epithelial cells as well as differentiated villus enterocytes
Tissue Specificity: Gut specific

Subcellular Location: Apical cell membrane Cell membrane, Lipid-anchor Cytoplasmic vesicle Myristoylation anchors the protein to the membrane, but the protein displays also calcium-dependent, reversible binding to lipid membranes (PubMed:30610115) Associated with the plasma membrane of undifferentiated, proliferating crypt epithelial cells as well as differentiated villus enterocytes (PubMed:1530946)

Storage and Stability: -20°C/1 year

Gene Name: ANXA13 ANX13

Protein Name: Annexin A13 (Annexin XIII) (Annexin-13) (Intestine-specific annexin) (ISA)

Mouse SwissProt Number: Q99JG3

Research Use Only