APBA1 Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS77828-50, BS77828-100 Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Swiss-Prot: Q02410 Host: Rabbit Reactivity: Human, Mouse Applications: IHC, IF/ICC All Applications: IHC,1:50 - 1:200 | IF/ICC,1:50 - 1:200 Background: The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008] Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Specificity: Unmodification Note: For research use only, not for use in diagnostic procedure. Extra Notes: Immunohistochemistry of paraffin-embedded mouse brain using APBA1 Rabbit pAb at dilution of 1:100. Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol., Immunofluorescence analysis of SH-SY5Y cells using APBA1 Rabbit pAb at dilution of 1:100. Blue: DAPI for nuclear staining., Immunofluorescence analysis of SH-SY5Y cells using APBA1 Rabbit pAb at dilution of 1:100. Blue: DAPI for nuclear staining. Alternative Name: D9S411E; LIN10; MINT1; X11; X11A; X11ALPHA; APBA1 Immunogen: Recombinant fusion protein of human APBA1(NP_001154.2). Conjugate: Unconjugated Modification: Unmodified