APC Monoclonal Antibody - BT-MCA2856

APC Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2856-50, BT-MCA2856-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

Research Areas: Cell Biology

Target Protein: APC

Applications: FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1F7G2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: APC

Immunogen: Purified recombinant fragment of human APC (AA: 2644-2843) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Molecular Weight (Da): 311.6kDa

UniProt Accession: P25054

Synonyms: GS, DP2, DP3, BTPS2, DP2.5, PPP1R46

GeneID: 324

Research Use Only