ApoE Monoclonal Antibody - BT-MCA0172

ApoE Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0172-50, BT-MCA0172-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

Research Areas: Cancer; Signal transduction; Metabolism; Cardiovascular; Neuroscience; Stem cells; Developmental biology

Target Protein: APOE

Applications: WB, IHC-p, IF, FCM, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Apolipoprotein E

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P02649; Mouse: P08226

Synonyms: APOE; Apolipoprotein E; Apo-E

GeneID: Human: 348

Research Use Only