APP Monoclonal Antibody - BT-MCA3013

APP Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3013-50, BT-MCA3013-100

Citations, Manuals and MSDS Available upon request.

Background: Amyloid precursor protein(APP) ,with 32-amino acid protein (about 35 kDa), is part of a super-family of transmembrane and secreted proteins. It appears to have a number of roles, including regulation of haemostasis and mediation of neuroprotection. APP undergoes alternative splicing, resulting in several isoforms . Proteolytic cleavage of amyloid precursor protein leads to the formation of the 4 kDa amyloid beta/A4 protein, which is present in human platelets. APP is also involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer patients.

Research Areas: Neuroscience, Signal Transduction

Target Protein: APP

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1B11F3

Host: Mouse

Isotype: Mouse IgG2a

Full Product Name: APP

Immunogen: Purified recombinant fragment of APP expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

UniProt Accession: P05067

Synonyms: APP

GeneID: 351

Research Use Only