APPL1 Polyclonal Antibody - E-AB-63089

APPL1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-63089-60, E-AB-63089-120, E-AB-63089-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: APPL1

Target Synonym: APPL1; APPL; DIP13alpha; MODY14

Research Areas: Cancer, Cell Biology, Developmental Biology, Neuroscience, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9UKG1

Background: The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human APPL1 (NP_036228.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 79kDa

Observed MW: 95kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only