Product Description

ARHGEF10 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65368-50, BS65368-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Swiss-Prot: O15013

Host: Rabbit

Reactivity: Human, Monkey

Applications: WB, IHC-P, IF (paraffin section), ELISA

All Applications: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Background: Rho guanine nucleotide exchange factor 10(ARHGEF10) Homo sapiens This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015],

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ARHGEF10 Polyclonal Antibody detects endogenous levels of ARHGEF10 protein.

Bioworld Molecular Weight: ~152 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of various cells using ARHGEF10 Polyclonal Antibody, Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ARHGEF10 Antibody. The picture on the right is blocked with the synthesized peptide., Western blot analysis of lysates from COS7 cells, using ARHGEF10 Antibody. The Lane on the right is blocked with the synthesized peptide.

Alternative Name: ARHGEF10; KIAA0294; Rho guanine nucleotide exchange factor 10

Immunogen: The antiserum was produced against synthesized peptide derived from human ARHGEF10. AA range:339-388

Conjugate: Unconjugated

Modification: Unmodified