Product Description

ARHGEF12 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65299-50, BS65299-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Swiss-Prot: Q9NZN5

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

All Applications: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Background: Rho guanine nucleotide exchange factor 12(ARHGEF12) Homo sapiens Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli working through G protein-coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein has been observed to form a myeloid/lymphoid fusion partner in acute myeloid leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014],

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: LARG Polyclonal Antibody detects endogenous levels of LARG protein.

Bioworld Molecular Weight: ~ 173 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of RAW264.7 cells using LARG Polyclonal Antibody, Western blot analysis of lysates from RAW264.7 cells, using ARHGEF12 Antibody. The Lane on the right is blocked with the synthesized peptide., Western blot analysis of the lysates from HUVECcells using ARHGEF12 antibody.

Alternative Name: ARHGEF12; KIAA0382; LARG; Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF

Immunogen: The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498

Conjugate: Unconjugated

Modification: Unmodified