Product Description

ARI1A Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31155-50, RA31155-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: AT-rich interaction domain 1A (ARID1A) Homo sapiens This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through eit

Reactivity: Human, Mouse

Host: Rabbit

Applications: IHC-p, IF (paraffin section)

Clonality: Polyclonal

Dilution: IHC-p 1:50-300

Molecular Weight: 251

Protein Molecular Weight (kDa): 251

Storage: -20°C/1 year

Human Gene ID: 8289

Human SwissProt Number: O14497

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only