ARK-1 Monoclonal Antibody - BT-MCA0182

ARK-1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0182-50, BT-MCA0182-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

Research Areas: Cell Biology; Signal Transduction; Cancer

Target Protein: AURKA

Applications: WB, IF, ICC, FCM, ELISA

Reactivity: Human,Rat,Monkey

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Aurora kinase A

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O14965; Mouse: P97477; Rat: P59241

Synonyms: AURKA; AIK; AIRK1; ARK1; AURA; AYK1; BTAK; IAK1; STK15; STK6; Aurora kinase A; Aurora 2; Aurora; IPL1-related kinase 1; ARK-1; Aurora-related kinase 1; hARK1; Breast tumor-amplified kinase; Serine; threonine-protein kinase 15; Serine; threonin

GeneID: Human: 6790

Research Use Only