Product Description

ARMCX2 (D347) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS2091-50, BS2091-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q7L311

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: The armadillo (ARM) repeat family of proteins are related to the Drosophila melanogaster armadillo protein, a protein essential for wingless signal transduction. ARM proteins are involved in a variety of processes such as cell migration, cell proliferation, tissue maintenance and tumorigenesis, and they also function in signal transduction and the maintenance of overall cell structure. ARMCX2 (armadillo repeat containing, X-linked 2), also known as ALEX2, is a 632 amino acid single-pass membrane protein that contains three ARM repeats and is highly expressed in testis, brain, ovary, heart, colon, spleen and prostate, where it is thought to play a role in tumor suppression. The gene encoding ARMCX2 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of ARMCX2 (D347) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 66 kDa

Specificity: ARMCX2 (D347) polyclonal antibody detects endogenous levels of ARMCX2 protein.

Alternative Name: Armadillo repeat-containing X-linked protein 2; ARM protein lost in epithelial cancers on chromosome X 2; Protein ALEX2; ARMCX2; ALEX2; KIAA0512

Immunogen: Synthetic peptide, corresponding to amino acids 312-368 of Human ARMCX2.

Conjugate: Unconjugated

Modification: Unmodified