ARRB1 Monoclonal Antibody - BT-MCA2250

ARRB1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2250-50, BT-MCA2250-100

Citations, Manuals and MSDS Available upon request.

Background: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.

Research Areas: Signal Transduction

Target Protein: ARRB1

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4E11B1

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: ARRB1

Immunogen: Purified recombinant fragment of human ARRB1 (AA: 89-268) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide.

Molecular Weight (Da): 47kDa

UniProt Accession: P49407

Synonyms: ARB1, ARR1

GeneID: 408

Research Use Only