ATF2 Monoclonal Antibody - BT-MCA2473

ATF2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2473-50, BT-MCA2473-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: ATF2

Applications: WB, IHC

Reactivity: Human, Mouse

Clonality: Monoclonal

Clone ID: 4F12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: ATF2

Immunogen: Purified recombinant fragment of human ATF2 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 55kDa

UniProt Accession: P15336

Synonyms: HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2

GeneID: 1386

Research Use Only