Product Description

ATF4 Rabbit Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS40308-50, BS40308-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P18848

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC ICC/IF, IP, FC

All Applications: WB 1:500~1:1000 IHC 1:50~1:200 ICC 1:100~1:500 IP 1:50 FC 1:50

Background: ATF4, an activating transcription factor/cAMP-response element-binding protein family member, functions in the PERK and eIF2α ER stress responsive pathway. ER stress represses the translation of the majority of mRNAs, but selectively stimulates the translation of certain mRNAs including that of ATF-4. Induced expression of ATF-4 increases the expression of genes critical for the recovery from ER stress.

Purification and Purity: Affinity-chromatography

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: ATF4 Antibody detects endogenous levels of ATF4

Bioworld Molecular Weight: 50kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of ATF4 expression in (1) HeLa cell lysate; (2) 3T3 cell lysate., Immunohistochemical analysis of paraffin-embedded mouse kidney, using ATF4 Antibody., Immunofluorescent analysis of 293 cells, using ATF4 Antibody.

Alternative Name: Cyclic AMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; DNA-binding protein TAXREB67;

Immunogen: A synthesized peptide derived from human ATF4

Conjugate: Unconjugated

Modification: Unmodified