ATP2B1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A18688-20, A18688-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified.
Category: Polyclonal Antibodies
Applications: WB, IF-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 135kDa
Observed Molecular Weight: 140kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 490
SWISS: P20020
Alternate Names: MRD66; PMCA1; PMCA1kb; ATP2B1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Neuroscience, Calcium Signaling.
NCBI Alias: ATP2B1
Research Use Only