Product Description

ATP5C1 (D165) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS3080-50, BS3080-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P36542

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200

Background: This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of ATP5C1 (D165) pAb in paraffin-embedded human thyroid gland tissue.

Bioworld Molecular Weight: ~ 33 kDa

Specificity: ATP5C1 (D165) polyclonal antibody detects endogenous levels of ATP5C1 protein.

Alternative Name: ATP synthase subunit gamma, mitochondrial; F-ATPase gamma subunit; ATP5C1; ATP5C; ATP5CL1

Immunogen: Synthetic peptide, corresponding to amino acids 150-200 of Human ATP5C1.

Conjugate: Unconjugated

Modification: Unmodified