ATP6V0A4 Monoclonal Antibody - BT-MCA2796

ATP6V0A4 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2796-50, BT-MCA2796-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing.

Research Areas: Others

Target Protein: ATP6V0A4

Applications: IHC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 9C9H9

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: ATP6V0A4

Immunogen: Purified recombinant fragment of human ATP6V0A4 (AA: 228-390) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 96.3kDa

UniProt Accession: Q9HBG4

Synonyms: A4, STV1, VPH1, VPP2, DRTA3, RTA1C, RTADR, ATP6N2, RDRTA2, ATP6N1B

GeneID: 50617

Research Use Only