ATR Monoclonal Antibody - BT-MCA2809

ATR Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2809-50, BT-MCA2809-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a serine/threonine kinase and DNA damage sensor, activating cell cycle checkpoint signaling upon DNA stress. The encoded protein can phosphorylate and activate several proteins involved in the inhibition of DNA replication and mitosis, and can promote DNA repair, recombination, and apoptosis. This protein is also important for fragile site stability and centrosome duplication. Defects in this gene are a cause of Seckel syndrome 1.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: ATR

Applications: FCM

Clonality: Monoclonal

Clone ID: 3G6D2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: ATR

Immunogen: Purified recombinant fragment of human ATR (AA: 366-550) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 301kDa

UniProt Accession: Q13535

Synonyms: FRP1, MEC1, SCKL, FCTCS, SCKL1

GeneID: 545

Research Use Only