Product Description

ATS4 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31226-50, RA31226-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ADAM metallopeptidase with thrombospondin type 1 motif 4 (ADAMTS4) Homo sapiens This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradatio

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 92

Protein Molecular Weight (kDa): 92

Storage: -20°C/1 year

Human Gene ID: 9507

Human SwissProt Number: O75173

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only