Product Description

ATS5 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31227-50, RA31227-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ADAM metallopeptidase with thrombospondin type 1 motif 5 (ADAMTS5) Homo sapiens This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 102

Protein Molecular Weight (kDa): 102

Storage: -20°C/1 year

Human Gene ID: 11096

Human SwissProt Number: Q9UNA0

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only