AURKA Monoclonal Antibody - BT-MCA3491

AURKA Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3491-50, BT-MCA3491-100

Citations, Manuals and MSDS Available upon request.

Background: Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.

Research Areas: Cell Biology

Target Protein: AURKA

Applications: WB, ICC, FCM

Reactivity: Human, Monkey, Rat

Clonality: Monoclonal

Clone ID: 1F8

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: AURKA

Immunogen: Purified recombinant fragment of human AURKA expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 48kDa

UniProt Accession: O14965

Synonyms: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, AURORA2, MGC34538, AURKA

GeneID: 6790

Research Use Only