AVR2B Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA31233-50, RA31233-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Purification Technology:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background: activin A receptor type 2B(ACVR2B) Homo sapiens Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. Th
Applications: WB, ELISA
Species Cross-Reactivity: Human, Mouse, Rat
Molecular Weight: 56
Protein Molecular Weight (kDa): 56
GeneID (Human): 93
SWISS: Q13705
Source: Rabbit
Immunogen: Synthesized peptide derived from human protein at AA range: 40-120
Category: Polyclonal
Research Use Only