Axl Monoclonal Antibody - BT-MCA0199

Axl Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0199-50, BT-MCA0199-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.

Research Areas: Signal transduction; Cancer; Cell biology

Target Protein: AXL

Applications: WB, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Tyrosine-protein kinase receptor UFO

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P30530; Mouse: Q00993

Synonyms: AXL; UFO; Tyrosine-protein kinase receptor UFO; AXL oncogene

GeneID: Human: 558

Research Use Only