AXL Monoclonal Antibody - BT-MCA4825

AXL Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4825-50, BT-MCA4825-100

Citations, Manuals and MSDS Available upon request.

Background: AXL: AXL receptor tyrosine kinase, also known as UFO, JTK11. Entrez Protein NP_001690. It is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.

Research Areas: Cell Biology

Target Protein: AXL

Applications: ICC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7E10

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: AXL

Immunogen: Purified recombinant extracellular fragment of human AXL fused with hIgGFc tag expressed in HEK293 cell line.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 97.4kDa

UniProt Accession: P30530

Synonyms: UFO, JTK11

GeneID: 558

Research Use Only