B7-H3/CD276 Polyclonal Antibody - E-AB-64054

B7-H3/CD276 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-64054-60, E-AB-64054-120, E-AB-64054-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: B7-H3/CD276

Target Synonym: CD276; 4Ig-B7-H3; B7-H3; B7H3; B7RP-2

Research Areas: Cancer, Immunology, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q5ZPR3

Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Concentration: 1mg/mL

Immunogen: A synthetic peptide of human B7-H3/CD276 (NP_001019907.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 33kDa/52kDa/57kDa

Observed MW: 115kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only