BACE2 Polyclonal Antibody - BT-AP06647

BACE2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06647-20, BT-AP06647-50, BT-AP06647-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimerandapos;s disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.

Research Areas: Cell biology; Neuroscience

Target Protein: BACE2

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Beta-secretase 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q9Y5Z0; Mouse: Q9JL18; Rat: Q6IE75

Synonyms: Beta-secretase 2;EC 3.4.23.45;Aspartic-like protease 56 kDa;Aspartyl protease 1;ASP1;Asp 1;Beta-site amyloid precursor protein cleaving enzyme 2;Beta-site APP cleaving enzyme 2;Down reg

GeneID: Human: 25825

Research Use Only