Product Description

BAP1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31266-50, RA31266-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: BRCA1 associated protein 1 (BAP1) Homo sapiens This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 80

Protein Molecular Weight (kDa): 80

Storage: -20°C/1 year

Human Gene ID: 8314

Human SwissProt Number: Q92560

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only