Product Description

Bc10 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES4569-50, ES4569-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a protein that reduces cell growth by stimulating apoptosis. Alternative splicing and the use of alternative promoters result in multiple transcript variants encoding the same protein. This gene is imprinted in brain where different transcript variants are expressed from each parental allele. Transcript variants initiating from the upstream promoter are expressed preferentially from the maternal allele, while transcript variants initiating downstream of the interspersed NNAT gene (GeneID:4826) are expressed from the paternal allele. Transcripts at this locus may also undergo A to I editing, resulting in amino acid changes at three positions in the N-terminus of the protein. [provided by RefSeq, Nov 2015],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: IF, ELISA

Alternate Names: BLCAP, BC10, Bladder cancer-associated protein, Bladder cancer 10 kDa protein, Bc10

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human BLCAP. AA range:38-87

Isotype: IgG

Target: Bc10

Specificity: Bc10 Polyclonal Antibody detects endogenous levels of Bc10 protein.

Dilution: WB 1:500-2000 Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Ubiquitous, Expressed in cervical tissues, Down-regulated in bladder invasive carcinoma, renal cell carcinoma and in primary cervical carcinoma,

Molecular Weight (Da): 10kD

Function: Similarity: Belongs to the BLCAP family
Tissue Specificity: Expressed in cervical tissues. Down-regulated during bladder cancer progression and in most cervical carcinomas

Subcellular Location: Membrane, Multi-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: BLCAP

Protein Name: Bladder cancer-associated protein

Mouse Gene ID: 53619

Mouse SwissProt Number: P62951

Rat Gene ID: 171113

Rat SwissProt Number: P62950

Research Use Only