BCL6 Monoclonal Antibody - BT-MCA3632

BCL6 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3632-50, BT-MCA3632-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: BCL6

Applications: WB, IHC, ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7A6D1

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: BCL6

Immunogen: Purified recombinant fragment of human BCL6 (AA: 507-706) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 78.8KDa

UniProt Accession: P41182

Synonyms: BCL5, LAZ3, BCL6A, ZNF51, ZBTB27

GeneID: 604

Research Use Only