BEST2 Polyclonal Antibody - BT-AP14450

BEST2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14450-20, BT-AP14450-50, BT-AP14450-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3andapos; ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon.

Research Areas: Signal transduction

Target Protein: BEST2

Applications: WB, IHC-p, IF

Reactivity: Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Bestrophin-2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q8NFU1; Mouse: Q8BGM5

Synonyms: Bestrophin-2; Bestrophin-2; Vitelliform macular dystrophy 2-like protein 1

GeneID: Human: 54831

Research Use Only