BEX3 Polyclonal Antibody - BT-AP14453

BEX3 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14453-20, BT-AP14453-50, BT-AP14453-100

Citations, Manuals and MSDS Available upon request.

Background: The nuclear export signal is required for export from the nucleus and the interactions with itself and p75NTR/NGFR.,May be a signaling adapter molecule involved in p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.,miscellaneous:Binds transition metals.,PTM:Ubiquitinated. Degraded by the proteasome.,Belongs to the BEX family.,subcellular location:Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria.,subunit:Self-associates. Interacts with 14-3-3 epsilon (YWHAE). Interacts with DIABLO/SMAC (By similarity). Binds to the DEATH domain of p75NTR/NGFR.,tissue specificity:Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.,

Research Areas: Cancer; Cell biology

Target Protein: NGFRAP1

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Protein BEX3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q00994; Mouse: Q9WTZ9; Rat: Q6PDU5

Synonyms: Protein BEX3;Brain-expressed X-linked protein 3;Nerve growth factor receptor-associated protein 1;Ovarian granulosa cell 13.0 kDa protein HGR74;p75NTR-associated cell death executor

GeneID: Human: 27018

Research Use Only