BID Monoclonal Antibody - BT-MCA0213

BID Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0213-50, BT-MCA0213-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8)| CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Research Areas: Cancer; Metabolism; Cell biology

Target Protein: BID

Applications: WB, IHC-p, IF, ICC, FCM, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: BH3-interacting domain death agonist

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P55957; Mouse: P70444

Synonyms: BID; BH3-interacting domain death agonist; p22 BID; BID

GeneID: Human: 637

Research Use Only