BID Monoclonal Antibody - BT-MCA3883

BID Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3883-50, BT-MCA3883-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.Tissue specificity: Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level)

Research Areas: Cell Biology

Target Protein: BID

Applications: WB, IHC, ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 3C5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: BID

Immunogen: Purified recombinant full length protein of human BID expressed in E. Coli

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 22kDa

UniProt Accession: P55957

Synonyms: FP497, MGC15319, MGC42355, BID

GeneID: 637

Research Use Only