BLK Monoclonal Antibody - BT-MCA3177

BLK Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3177-50, BT-MCA3177-100

Citations, Manuals and MSDS Available upon request.

Background: Blk is a Src family protein tyrosine kinase expressed in all stages of B cell development . Activation of B cells by various ligands is accompanied by activation of Blk . It has been suggested that Blk is involved in the control of B cell differentiation and proliferation . Blk transcripts have also been detected in human thymocytes, but not in mature T cells, implicating that Blk may play an important role in thymopoiesis . Blk function may be redundant, however, as mice that do not express Blk are not impaired with respect to B cell development and immune response .

Research Areas: Cell Biology

Target Protein: BLK

Applications: ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 1E6

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: BLK

Immunogen: Purified recombinant fragment of human BLK expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 58kDa

UniProt Accession: P51451

Synonyms: MODY11, MGC10442, BLK

GeneID: 640

Research Use Only