BMP3B Polyclonal Antibody - BT-AP14467

BMP3B Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP14467-20, BT-AP14467-50, BT-AP14467-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This promotes neural repair after stroke. Additionally, this protein may act as a tumor suppressor and reduced expression of this gene is associated with oral cancer.

Research Areas: Cancer; Cell biology; Signal transduction; Stem cells

Target Protein: GDF10

Applications: WB, ELISA

Reactivity: Human, Rat, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Bone morphogenetic protein 3B

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P55107; Mouse: P97737; Rat: P55108

Synonyms: Bone morphogenetic protein 3B;BMP-3B;Bone-inducing protein;BIP;Growth/differentiation factor 10;GDF-10

GeneID: Human: 2662

Research Use Only