BNP Monoclonal Antibody - BT-MCA0228

BNP Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0228-50, BT-MCA0228-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.

Research Areas: Cardiovascular; Signal transduction

Target Protein: NPPB

Applications: IHC-p, IF, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Natriuretic peptides B

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P16860; Mouse: P40753

Synonyms: NPPB; Natriuretic peptides B; Gamma-brain natriuretic peptide

GeneID: Human: 4879

Research Use Only