Product Description

BORG5 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES9517-50, ES9517-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Target: BORG5

Specificity: BORG5 Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Endothelial and bone marrow stromal cells,

Observed Band (KD): 43kD

Function: Domain: The CRIB domain mediates interaction with CDC42
Function: Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts
Similarity: Belongs to the BORG/CEP family
Similarity: Contains 1 CRIB domain
Subunit: Interacts with RHOQ and CDC42, in a GTP-dependent manner
Tissue Specificity: Endothelial and bone marrow stromal cells

Subcellular Location: Endomembrane system, Peripheral membrane protein Cytoplasm, cytoskeleton

Storage and Stability: -20°C/1 year

Gene Name: CDC42EP1 BORG5 CEP1 MSE55

Protein Name: Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55)

Mouse SwissProt Number: Q91W92

Rat SwissProt Number: A1A5P0

Research Use Only