C-CBL Monoclonal Antibody - BT-MCA3666

C-CBL Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3666-50, BT-MCA3666-100

Citations, Manuals and MSDS Available upon request.

Background: The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.

Research Areas: Others

Target Protein: C-CBL

Applications: WB, IHC, ICC, FCM

Reactivity: Human, Mouse, Rat

Clonality: Monoclonal

Clone ID: 3B12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: C-CBL

Immunogen: Purified recombinant fragment of human C-CBL expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 120kDa

UniProt Accession: P22681

Synonyms: CBL, CBL2, NSLL, C-CBL, RNF55

GeneID: 867

Research Use Only