Product Description

C/EBP γ Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES4503-50, ES4503-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: CEBPG, CCAAT/enhancer-binding protein gamma, C/EBP gamma

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human CEBPG. AA range:31-80

Isotype: IgG

Target: C/EBP γ

Specificity: C/EBP γ Polyclonal Antibody detects endogenous levels of C/EBP γ protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Placenta, T-cell, Trachea,

Observed Band (KD): 22kD

Fields: Tuberculosis

Function: Function: Transcription factor that binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene. Might change the DNA-binding specificity of other transcription factors and recruit them to unusual DNA sites
Similarity: Belongs to the bZIP family. C/EBP subfamily
Similarity: Contains 1 bZIP domain
Subunit: Binds DNA as a dimer and can form stable heterodimers with C/EBP alpha and beta and with Fos protein

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: CEBPG

Protein Name: CCAAT/enhancer-binding protein gamma

Mouse Gene ID: 12611

Mouse SwissProt Number: P53568

Rat Gene ID: 25301

Rat SwissProt Number: P26801

Research Use Only