C-Kit Monoclonal Antibody - BT-MCA3136

C-Kit Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3136-50, BT-MCA3136-100

Citations, Manuals and MSDS Available upon request.

Background: C-kit (CD117, 145kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

Research Areas: Others

Target Protein: C-Kit

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 8D7

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: C-Kit

Immunogen: Purified recombinant fragment of C-kit expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 145kDa

UniProt Accession: P10721

Synonyms: PBT, SCFR, C-Kit, CD117, KIT

GeneID: 3815

Research Use Only