C-MYC Monoclonal Antibody - BT-MCA2321

C-MYC Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2321-50, BT-MCA2321-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]

Research Areas: Others

Target Protein: C-MYC

Applications: IHC, FCM

Clonality: Monoclonal

Clone ID: 6H11F6

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: C-MYC

Immunogen: Purified recombinant fragment of human C-MYC (AA: (290-439)) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 32.1|57|48.8kDa

UniProt Accession: P01106

Synonyms: MRTL, MYCC, c-Myc, bHLHe39

GeneID: 4609

Research Use Only