c-Rel Monoclonal Antibody - BT-MCA0243

c-Rel Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0243-50, BT-MCA0243-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Areas: Epigenetics and nuclear signaling; Cancer; Signal transduction

Target Protein: REL

Applications: WB, IHC-p, IF, ICC, ELISA

Reactivity: Human,Mouse

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Proto-oncogene c-Rel

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q04864; Mouse: P15307

Synonyms: REL; Proto-oncogene c-Rel

GeneID: Human: 5966

Research Use Only