CAC1A Polyclonal Antibody - BT-AP06997

CAC1A Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP06997-20, BT-AP06997-50, BT-AP06997-100

Citations, Manuals and MSDS Available upon request.

Background: Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas, the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1A subunit, which is predominantly expressed in neuronal tissue. Mutations in this gene are associated with 2 neurologic disorders, familial hemiplegic migraine and episodic ataxia 2. This gene also exhibits

Research Areas: Cancer; Metabolism; Neuroscience

Target Protein: CACNA1A

Applications: IHC-p, IF

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Voltage-dependent P/Q-type calcium channel subunit alpha-1A

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O00555; Mouse: P97445; Rat: P54282

Synonyms: Voltage-dependent P/Q-type calcium channel subunit alpha-1A;Brain calcium channel I;BI;Calcium channel, L type, alpha-1 polypeptide isoform 4;Voltage-gated calcium channel subunit alpha Cav2.1

GeneID: Human: 773

Research Use Only