Product Description

CaIPLA2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS66138-50, BS66138-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regμlating transmembrane ion flux in glucose-stimμlated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regμlation of F-actin polymerization at the pseudopods. Isoform ankyrin-iPLA2-1 and isoform ankyrin-iPLA2-2, which lack the catalytic domain, are probably involved in the negative regμlation of iPLA2 activity.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA, IHC, IF

Alternate Names: group VI iPLA2, 85 kDa calcium independent phospholipase A2, 85 kDa calcium-independent phospholipase A2, CaI PLA2, CaI-PLA2, CaIPLA2, Calcium independent phospholipase A2, Cytosolic calcium independent phospholipase A2, Group VI phospholipase A2, GVI, GVI PLA2, INAD1, iPLA(2)beta, iPLA2, IPLA2 VIA, iPLA2beta, NBIA2A, NBIA2B, PA2G6_HUMAN, PARK14, Patatin like phospholipase domain containing 9, Patatin like phospholipase domain containing protein 9, Phospholipase A2 calcium independent, Phospholipase A2 calcium independent group VI A, Phospholipase A2 group VI, Phospholipase A2 group VI cytosolic calcium independent, PLA2, PLA2G6, PNPLA9, PLPL9_HUMAN

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human CaIPLA2/PLA2G6: 651-750/806

Dilution: WB: 1:500-1:2000
ELISA: 1:5000-1:10000
IHC: 1:100-1:500
IF: 1:100-1:500

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CaIPLA2 Polyclonal Antibody detects endogenous levels of CaIPLA2 protein.

Molecular Weight: ~ 90 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O60733

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only