Product Description

CALML6 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-17762-60, E-AB-17762-120, E-AB-17762-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CALML6

Target Synonym: CAGLP; Calglandulin-like protein; CALGP; CALL6; CALML6; Calmodulin like 6; Calmodulin-like protein 6; EF-hand protein; OTTHUMP00000001117; OTTHUMP00000179025; RP1-140A9.2

Research Areas: Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8TD86

Background: The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), a universal calcium sensor. CaM directly modulates the activity of protein kinases and phosphatases, ion channels and nitric oxide synthetases and is generally involved in such diverse processes as cell proliferation, endocytosis, cellular adhesion, protein turnover and smooth muscle contraction. CALML6 (calmodulin-like 6), also known as CAGLP or CALGP, is a 181 amino acid protein that contains four EF-hand domains and shares functional similarity with CaM. Localized to both the nucleus and the cytoplasm, CALML6 is expressed in heart, prostate, ovary, thymus and bone marrow where it may regulate calcium-related events.

Concentration: 0.5 mg/mL

Immunogen: Synthetic peptide of human CALML6

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only