Calpain small subunit 1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A6539-20, A6539-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 28kDa
Observed Molecular Weight: 28kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 826
SWISS: P04632
Alternate Names: CANP; CDPS; CSS1; CANPS; CAPN4; CALPAIN4; Calpain small subunit 1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Immunology Inflammation, T Cell Receptor Signaling Pathway, Neuroscience, Calcium Signaling.
NCBI Alias: CAPNS1
Research Use Only