Product Description

CAMLG Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA31379-50, RA31379-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: calcium modulating ligand (CAMLG) Homo sapiens The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008],

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 32

Protein Molecular Weight (kDa): 32

Storage: -20°C/1 year

Human Gene ID: 819

Human SwissProt Number: P49069

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only